A hand holding a jar of Trelli Relivaid against a soft blue and cream gradient

Naturally derived cramp relief, developed by doctors.

Three bioactives that work where cramps start and where you feel them, so you can take it the moment they hit and as often as they come back.

4.8(49)
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71% of women have cramps.

It is the most common thing women treat, and the thing they most often treat with something they would rather not be taking. Relivaid is naturally derived and formulated by doctors, so it is the rare option you can feel good about reaching for the moment cramps start.

A hand holding up a jar of Trelli Relivaid, label facing the camera

5 in 10 of women don't use anything for their period pain

A single maroon Relivaid capsule balanced on a fingertip
Relivaid™
Relivaid™
Relivaid™
Relivaid™
Relivaid™
Relivaid™

Relivaid™Fast-Acting Cramp Relief

(49)

Fast, drug-free relief for period cramps, formulated by doctors and gentle enough on your stomach to take the moment cramps start.

  • Menstrual cramps
  • PMS headaches
  • Lower back ache
  • Joint and muscle aches
How would you like to buy?

How would you like to buy?

1 Bottle

$45.00
per bottle

2 Bottles

$40.50
per bottle
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FREE SHIPPING

3 Bottles

$38.25
per bottle
SAVE 15%
FREE SHIPPING
  • 30-day money-back guarantee
  • Formulated by doctors
  • Naturally derived bioactives
  • Rapid absorption
  • Made in the USA

Real feedback from our customers.

Read all reviews
“I took my first dose of Relivaid today for back and cramp pain and was very impressed with the speed and the effectiveness of the pain relief.”
AMANDA F.
“I found this product to be just as effective as a painkiller when it comes to PMS headaches and period cramps!”
AXELLE L.
“These helped my cramps immensely, along with getting rid of my headache that goes along with it. Fast working and allowed me to get through the rest of my day.”
SANDRA D.
“Works fantastic don't ever want to be without it. I even got my daughter to switch to using it too.”
LYNN D.
“This product worked exceptionally well on my daughters hard to relieve menstrual cramps. About an hour later she was feeling relief.”
VERIFIED BUYER
“The only thing that helps with my cramps.”
ANNE

Our recommendation for Relivaid and cramps.

Relivaid works best when you start it before the cramps do, and it is safe to keep taking through the day for as long as you need it.

A jar of Trelli Relivaid beside a glass of water

Start Relivaid the day before cramps hit

Starting Relivaid the day before your cramps start helps to reduce prostaglandin buildup in the uterus, which are the cause behind painful cramps the next day.

Two Relivaid capsules beside a glass of water

Continue to take as needed for fast relief

In an observational study, most women had cramp relief in under 60 minutes with Relivaid, with the majority having relief in as little as 30 minutes.

A woman taking a Relivaid capsule with water

Use Relivaid up to 3 times per day

Relivaid is safe to take up to three times per day and can be repeated for continuous support to ensure your cramps aren't affecting your day.

Dr. Kennard, DO, OB-GYN

Dr. Kennard, DO, OB-GYN

Triple-board certified, Trelli Medical Advisor

If you are pregnant, breastfeeding or taking other medication, speak to your healthcare provider first.

Three actives, two places cramps hurt.

Before your period the lining of the uterus breaks down and COX enzymes, chiefly COX-2, produce prostaglandins that make the muscle contract and turn up the pain signal. Relivaid works on both halves of that, at the source and at the nerve.

Macro photograph of freshly cut ginger slices

Bio-Optimized Gingerols

At the source · Inflammation

Gingerols reduce prostaglandin production in the uterus, so there is less for the muscle to contract against. Ours uses a proprietary delivery system that carries far more of the active across the lipid membrane than ordinary ginger manages.

A sculptural model of the PEA molecule

Phospholipid-Bound PEA

At the nerve · Neural signalling

PEA is a compound your body already makes. It calms the nerve signalling that keeps cramps loud once they have started, and binding it to phospholipids markedly improves how much of it you absorb.

A ripe red coffee cherry, shown as a scale reference for the low caffeine dose in Relivaid

USP-Grade Caffeine

For speed · Onset

A modest dose, less than half a cup of coffee, that speeds up how quickly the other two actives reach you. It is there for onset rather than as a stimulant.

With Relivaid, we check every box.

Relivaid
Natural Remedies
Other OTC
Liver Friendly
Yes
No
No
GI Friendly
Yes
Yes
No
Fast-Acting
Yes
No
Yes
Safe For Longer Use
Yes
Yes
No
Third Party Tested
Yes
No
No
Formulated By MDs & Integrative Experts
Yes
No
No
Meet our medical board.

Relivaid is supported by Trelli’s Medical Advisory Board made up of physicians, scientists, and leading experts. Meet the people behind our formulas.

Dr. Anne Kennard

DO, OBGYN, FACLM, Dipl-ABOIM

Women's HealthIntegrative Medicine

Board-certified OB-GYN and integrative medicine physician with deep expertise in women's hormonal health and lifestyle medicine.

Board-certified OB-GYN and integrative medicine physician with deep expertise in women's hormonal health and lifestyle medicine.

Dr. Stephen Dahmer

MD

FormulationIntegrative Medicine

Medical Director at the Andrew Weil Center for Integrative Medicine. Pioneering the clinical integration of conventional and natural therapies.

Medical Director at the Andrew Weil Center for Integrative Medicine. Pioneering the clinical integration of conventional and natural therapies.

Dr. Jacqueline Jacques

ND

FormulationDelivery System Science

Former Chief Research Officer at Thorne with 15+ years of leading evidence-based formulation at the health and wellness industry's highest standard.

Former Chief Research Officer at Thorne with 15+ years of leading evidence-based formulation at the health and wellness industry's highest standard.

Dr. Lisa Offringa

PhD, Medical and Nutritional Ethnobotany

Botanical SciencePlant Medicine

Expert in the science of botanical ingredients, bridging traditional plant medicine with modern clinical evidence and precision formulation.

Expert in the science of botanical ingredients, bridging traditional plant medicine with modern clinical evidence and precision formulation.

Dr. Margo Bachman

DACM, L.Ac., CFMP

Women’s HealthChinese Herbal Medicine

Doctor of Acupuncture and Chinese Medicine specializing in women's hormonal health, herbal formulation, and functional medicine approaches.

Doctor of Acupuncture and Chinese Medicine specializing in women's hormonal health, herbal formulation, and functional medicine approaches.

Dr. Robert Bonakdar

MD, FACN, ABOIM, FAAFP

Integrative MedicinePain Management

Director of Pain Management at Scripps Center for Integrative Medicine and is a nationally recognized leader in evidence based integrative pain care.

Director of Pain Management at Scripps Center for Integrative Medicine and is a nationally recognized leader in evidence based integrative pain care.

Dr. Stacey Bell

DSc, Nutrition

Clinical NutritionProduct Development

Former faculty at Harvard Medical School with decades of expertise in clinical nutrition science and evidence-based nutritional product development.

Former faculty at Harvard Medical School with decades of expertise in clinical nutrition science and evidence-based nutritional product development.

Dr. Igor Koturbash

MD, PhD, Biomolecular Sciences

ToxicologySafety

Leading researcher in ingredient safety and toxicology, ensuring every compound meets rigorous clinical standards before inclusion in any formulation.

Leading researcher in ingredient safety and toxicology, ensuring every compound meets rigorous clinical standards before inclusion in any formulation.

Dr. Tina Kaczor

ND, FABNO

Clinical ResearchNaturopathic Oncology

Former Editor-in-Chief of the Natural Medicine Journal, a leading voice in evidence-based integrative, and clinical research across naturopathic oncology.

Former Editor-in-Chief of the Natural Medicine Journal, a leading voice in evidence-based integrative, and clinical research across naturopathic oncology.

Cramp questions, honest answers.

When in my cycle should I take it?

Most women take it at the first cramp, and a single dose is enough for it to work, so you do not have to plan around it. If you know your cramps are coming, starting a few days before your period helps reduce them further, because the gingerols lower prostaglandin production in the uterus and there is less of the signal that drives the cramping to begin with.

How fast will I feel it?

Average time to relief is 30 minutes, based on real customer data. Most people notice something within 30 to 60 minutes depending on the day and how early they take it.

Can I take this instead of what I usually take for cramps?

Many customers use Relivaid in place of what they usually reach for, and it is formulated to match that level of relief rather than exceed it. If your cramps are severe enough that nothing over the counter has helped, talk to your doctor. We would rather tell you that than sell you something that disappoints.

Will it help my PMS headaches and back ache too?

Yes. The same formulation supports the headaches, low back ache and body aches that arrive alongside your period, not only the cramps themselves.

Can I take it every day of my period?

Yes. Relivaid is safe to take daily or as needed. If you experience ongoing or persistent pain, we recommend consulting with a healthcare provider to determine the best long-term approach for your individual health needs.

Can I take it with other supplements or medications?

In general, Trelli products are safe to use alongside most supplements and medications. However, because everyone’s health profile is unique, we recommend speaking with your healthcare provider before combining any products.

Is Relivaid allergen free?

Yes. Relivaid is free of all major allergens including gluten, and it is a vegan product.

Can I take it if I am pregnant or breastfeeding?

If you are pregnant or breastfeeding, please consult your healthcare professional before use. While our ingredients are naturally derived and well-tolerated, your provider can best guide what is appropriate for your individual needs.