Naturally Derived Cramp Relief that Works Fast.

Naturally Derived Cramp Relief that Works Fast.

Drug-free, OBGYN-backed relief for cramps, PMS headaches, and the symptoms that travel with your period.

Relivaid™
Relivaid™
Relivaid™
Relivaid™
Relivaid™
Relivaid™

Relivaid™Fast-Acting Cramp Relief

(43)

Fast-acting, drug-free relief for period cramps, formulated by doctors and gentle enough on your stomach to take the moment cramps start.

  • Drug-free formulation
  • Naturally derived bioactives, without the side effects
  • Backed by OBGYNs and women's health experts
  • Helps with cramps and other PMS symptoms
  • Safe to use as often as needed without harming your stomach
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What women say about Relivaid.

Meet our medical board.

Relivaid is supported by Trelli’s Medical Advisory Board made up of physicians, scientists, and leading experts. Meet the people behind our formulas.

Dr. Anne Kennard

DO, OBGYN, FACLM, Dipl-ABOIM

Women's HealthIntegrative Medicine

Board-certified OB-GYN and integrative medicine physician with deep expertise in women's hormonal health and lifestyle medicine.

Board-certified OB-GYN and integrative medicine physician with deep expertise in women's hormonal health and lifestyle medicine.

Dr. Stephen Dahmer

MD

FormulationIntegrative Medicine

Medical Director at the Andrew Weil Center for Integrative Medicine. Pioneering the clinical integration of conventional and natural therapies.

Medical Director at the Andrew Weil Center for Integrative Medicine. Pioneering the clinical integration of conventional and natural therapies.

Dr. Jacqueline Jacques

ND

FormulationDelivery System Science

Former Chief Research Officer at Thorne with 15+ years of leading evidence-based formulation at the health and wellness industry's highest standard.

Former Chief Research Officer at Thorne with 15+ years of leading evidence-based formulation at the health and wellness industry's highest standard.

Dr. Lisa Offringa

PhD, Medical and Nutritional Ethnobotany

Botanical SciencePlant Medicine

Expert in the science of botanical ingredients, bridging traditional plant medicine with modern clinical evidence and precision formulation.

Expert in the science of botanical ingredients, bridging traditional plant medicine with modern clinical evidence and precision formulation.

Dr. Margo Bachman

DACM, L.Ac., CFMP

Women’s HealthChinese Herbal Medicine

Doctor of Acupuncture and Chinese Medicine specializing in women's hormonal health, herbal formulation, and functional medicine approaches.

Doctor of Acupuncture and Chinese Medicine specializing in women's hormonal health, herbal formulation, and functional medicine approaches.

Dr. Robert Bonakdar

MD, FACN, ABOIM, FAAFP

Integrative MedicinePain Management

Director of Pain Management at Scripps Center for Integrative Medicine and is a nationally recognized leader in evidence based integrative pain care.

Director of Pain Management at Scripps Center for Integrative Medicine and is a nationally recognized leader in evidence based integrative pain care.

Dr. Stacey Bell

DSc, Nutrition

Clinical NutritionProduct Development

Former faculty at Harvard Medical School with decades of expertise in clinical nutrition science and evidence-based nutritional product development.

Former faculty at Harvard Medical School with decades of expertise in clinical nutrition science and evidence-based nutritional product development.

Dr. Igor Koturbash

MD, PhD, Biomolecular Sciences

ToxicologySafety

Leading researcher in ingredient safety and toxicology, ensuring every compound meets rigorous clinical standards before inclusion in any formulation.

Leading researcher in ingredient safety and toxicology, ensuring every compound meets rigorous clinical standards before inclusion in any formulation.

Dr. Tina Kaczor

ND, FABNO

Clinical ResearchNaturopathic Oncology

Former Editor-in-Chief of the Natural Medicine Journal, a leading voice in evidence-based integrative, and clinical research across naturopathic oncology.

Former Editor-in-Chief of the Natural Medicine Journal, a leading voice in evidence-based integrative, and clinical research across naturopathic oncology.

Helps with cramps and other PMS symptoms.

Most women taking Relivaid for cramps are dealing with the headache, the low back ache and the general heaviness that arrives alongside them. It is one formulation for the whole cluster rather than a cramp-only fix.

PMS headaches

The headache that turns up in the days before your period, and the one that arrives with it. Relivaid supports pain wherever it is firing, not only in the uterus.

Lower back and hip ache

Prostaglandins do not stay in one place. As they reach the rest of your body the ache travels, which is why the same dose helps there too.

Body aches and inflammation

Gingerols work on inflammation at the source, so Relivaid keeps doing something well past the first sharp hours of your period.

How fast Relivaid works.

83% said Relivaid worked as well or better than what they normally take.*

*Based on a conducted sample test of 41 people

Early Results on Relivaid

30 minutes


“The pain from my period cramps really did go away fast and almost entirely.”

- Colombe F.

How Relivaid works on cramps.

Before your period the lining of the uterus breaks down and COX enzymes, chiefly COX-2, produce prostaglandins. PGF2-alpha makes the muscle contract and PGE2 turns up the pain signal. Relivaid works on both halves of that, at the source and at the nerve.

01AT THE SOURCE

Works where cramps begin.

Bio-Optimized Gingerols

Inflammation

Gingerols reduce prostaglandin production in the uterus, so there is less for the muscle to contract against.

→ HOW IT WORKS

  • Reduces prostaglandin production in the uterus
  • Acts on COX enzymes, chiefly COX-2
  • Eases the inflammation that travels with your period
02AT THE NERVE

Works on the pain signal.

Phospholipid-Bound PEA

Neural signaling

PEA is a compound your body already makes. It calms the nerve signalling that keeps cramps loud once they start.

→ HOW IT WORKS

  • Activates PPAR-alpha receptors
  • Calms sensitised pain nerves
  • Turns down inflammatory signalling

USP-Grade Caffeine

Delivery and onset

A modest dose of caffeine, less than half a cup of coffee, that speeds up absorption so relief starts sooner.

→ HOW IT WORKS

  • Speeds absorption of the other two actives
  • Adenosine receptor antagonism
  • Not there as a stimulant
03FOR SPEED

Works sooner.

What's in Relivaid?

BIO-OPTIMIZED
2 PAIN PATHWAYS
FAST ACTING
DOCTOR FORMULATED

PEA Complex

Also known as Palmitoylethanolamide, a lipid mediator the body naturally produces to help regulate pain and inflammation.

HOW & WHY IT WORKS

→ How it works:

By activating PPAR-a receptors and calming neuro-inflammatory activity.

→ Why it works:

Trelli uses a PEA complex combined with phospholipids for significant improvements in absorption.

Amphiphilic Ginger

Standardized to Gingerol and Shogaol molecules

HOW & WHY IT WORKS

→ How it works:

Supports the body by responding to inflammation by interacting with the COX-2 enzyme that drives prostaglandin production.

→ Why it works:

Trelli ginger utilizes a proprietary non-polar, polar sandwiching technology for improved transmission of bioactive components across the lipid membrane.

Low-Dose Caffeine

Equal to a cup of green tea.

HOW & WHY IT WORKS

→ How & why it works:

Works complementary with the two other ingredients and blocks adenosine receptors in the brain, constricting dilated blood vessels.

Hero Image

PEA Complex

Also known as Palmitoylethanolamide, a lipid mediator the body naturally produces to help regulate pain and inflammation.

HOW & WHY IT WORKS

→ How it works:

By activating PPAR-a receptors and calming neuro-inflammatory activity.

→ Why it works:

Trelli uses a PEA complex combined with phospholipids for significant improvements in absorption.

Amphiphilic Ginger

Standardized to Gingerol and Shogaol molecules

HOW & WHY IT WORKS

→ How it works:

Supports the body by responding to inflammation by interacting with the COX-2 enzyme that drives prostaglandin production.

→ Why it works:

Trelli ginger utilizes a proprietary non-polar, polar sandwiching technology for improved transmission of bioactive components across the lipid membrane.

Low-Dose Caffeine

Equal to a cup of green tea.

HOW & WHY IT WORKS

→ How & why it works:

Works complementary with the two other ingredients and blocks adenosine receptors in the brain, constricting dilated blood vessels.

With Relivaid, we check every box.

Relivaid
Natural Remedies
Other OTC
Liver Friendly
Yes
No
No
GI Friendly
Yes
Yes
No
Fast-Acting
Yes
No
Yes
Safe For Longer Use
Yes
Yes
No
Third Party Tested
Yes
No
No
Formulated By MDs & Integrative Experts
Yes
No
No

Cramp questions, honest answers.

When in my cycle should I take it?

Most women take it at the first cramp, and a single dose is enough for it to work, so you do not have to plan around it. If you know your cramps are coming, starting a few days before your period helps reduce them further, because the gingerols lower prostaglandin production in the uterus and there is less of the signal that drives the cramping to begin with.

How fast will I feel it?

Average time to relief is 30 minutes, based on real customer data. Most people notice something within 30 to 60 minutes depending on the day and how early they take it.

Can I take this instead of what I usually take for cramps?

Many customers use Relivaid in place of what they usually reach for, and it is formulated to match that level of relief rather than exceed it. If your cramps are severe enough that nothing over the counter has helped, talk to your doctor. We would rather tell you that than sell you something that disappoints.

Will it help my PMS headaches and back ache too?

Yes. The same formulation supports the headaches, low back ache and body aches that arrive alongside your period, not only the cramps themselves.

Can I take it every day of my period?

Yes. Relivaid is safe to take daily or as needed. If you experience ongoing or persistent pain, we recommend consulting with a healthcare provider to determine the best long-term approach for your individual health needs.

Can I take it with other supplements or medications?

In general, Trelli products are safe to use alongside most supplements and medications. However, because everyone’s health profile is unique, we recommend speaking with your healthcare provider before combining any products.

Is Relivaid allergen free?

Yes. Relivaid is free of all major allergens including gluten, and it is a vegan product.

Can I take it if I am pregnant or breastfeeding?

If you are pregnant or breastfeeding, please consult your healthcare professional before use. While our ingredients are naturally derived and well-tolerated, your provider can best guide what is appropriate for your individual needs.